In his best game of the season -- last week versus the Arizona Cardinals -- Isaac Guerendo finished with 2.2 fantasy points.
Isaac Guerendo had a 76-yard run in the fourth quarter to help the San Francisco 49ers defeat the Seattle Seahawks, 36-24.
The 49ers running back room is depleted after Jordan Mason suffered a shoulder injury on "Thursday Night Football." ...
Deebo Samuel shared a playful response to Isaac Guerendo after the 49ers rookie running back didn't score his first NFL ...
The 49ers are extremely hopeful about rookie running back Isaac Guerendo. He's a bit of a project considering he never ...
Guerendo's big play has created quite the debate in the 49ers locker room. The rookie running back claims he was told to ...
San Francisco's Isaac Guerendo seals the 49ers' win with a 76-yard run in the final two minutes, then Kyle Juszczyk scores to ...
The 49ers were already down Christian McCaffrey. Now they’re down Jordan Mason with Isaac Guerendo replacing him in the ...