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Three of the most commonly used, which were the focus of the new study, are BCRP, MRP2, and PgP. For this study, Traverso and his colleagues adapted a tissue model they had developed in 2020 to ...

For example, Mct1, UGT, PST, GST, and MRP2 distribution favors the duodenum and jejunum over the ileum. Rate of gastric emptying Slowed gastric emptying may reduce the rate of drug absorption ...

Bart et al. have studied the localization of the efflux pumps P-gp, BCRP, MRP1 and MRP2 to better understand the role of the BTB. Immunohistochemical staining for the four efflux pumps was ...

Addressing dyslipidemia is crucial to reducing the burden imposed by cardiovascular disease. However, many current statins have major limitations. Moreover, innovative treatments need to address ...