We employed Monocle2 (Qiu et al., 2017) to discover the differentiation trajectory for T cells and endothelial cells. The top 2,000 DEGs between the cell subgroups were used to create the DDRTree.

Gene set variation analysis (GSVA) was performed on the HALLMARK gene sets from MSigDB. Monocle 2 was used to reconstruct differentiation trajectories, and cytokine signature enrichment analysis was ...

Picture it: An acne-clad, pasty middle schooler with frizzy curls and full set of fangs (two of those are still true; I’ll let you guess which ones). Her middle-class parents take her and her ...

Watch the full official trailer for Smile 2, an upcoming thriller horror film distributed by Paramount Pictures. About to embark on a new world tour, global pop sensation Skye Riley (Naomi Scott ...

Oli Welsh is senior editor, U.K., providing news, analysis, and criticism of film, TV, and games. He has been covering the business & culture of video games for two decades. Nintendo, notoriously ...

Highlights from London Fashion Week and a report from the Habitare trade fair in Finland. We leaf through the pages of the magazine’s latest mobility special, including our dream for the perfect train ...

Professor Paul Romer won the 2018 Nobel Prize in Economic Sciences for his work integrating technological innovations into long-run macroeconomic analysis. In May, Romer spoke to Monocle Radio on the ...

When is the Path of Exile 2 release date? Path of Exile 2 has now evolved from its initial role as effectively a large expansion to become its own full game, with completely new mechanics, classes ...

Joker 2 (officially titled Joker: Folie à Deux) is only a few weeks away, where we'll finally see Joaquin Phoenix reprise his role as the clown prince of crime alongside pop idol Lady Gaga as his ...

The Nintendo Switch 2 hasn't officially been announced but it's not unreasonable to expect news directly from Nintendo sometime this year. After all, a company statement from president Shuntaro ...