Journal of Clinical Oncology - ASCO Publications
WEBOct 1, 2024 · A world where cancer is prevented or cured. Founded in 1964, the American Society of Clinical Oncology, Inc. (ASCO®) is committed to making a world of difference in cancer care. Through research, education, and promotion of the highest-quality, equitable patient care, ASCO works to conquer cancer and create a world where cancer is …
Management of Immune-Related Adverse Events in Patients …
WEBImmunotherapy has revolutionized the treatment of many different types of cancers. Immune checkpoint inhibitors (ICPis) targeting cytotoxic T-lymphocyte–associated antigen-4 (CTLA-4), programmed cell death-1 (PD-1), and PD ligand 1 (PD-L1) work by preventing the receptors and ligands from binding to each other, thereby disrupting signaling so that …
Current and Future Management of HER2-Positive Metastatic …
WEBJun 2, 2021 · Advanced breast cancer with overexpression and/or amplification of human epidermal growth factor receptor 2 (HER2) is a clinically aggressive subtype with poor survival outcomes. 1,2 However, with the introduction of trastuzumab, the survival rates have greatly improved. 1 Trastuzumab binds to the extracellular domain IV of HER2 …
Treatment of Metastatic Colorectal Cancer: ASCO Guideline
WEBOct 17, 2022 · Perioperative chemotherapy is recommended for a total preoperative and postoperative duration of 6 months, on the basis of total duration of chemotherapy in the EORTC 40983 trial. 64. Table 10. Perioperative Chemotherapy Versus Surgery Alone for Patients With Liver Metastases From Colorectal Cancer 22. Open in viewer.
Current Management of Appendiceal Neoplasms | American …
WEBMar 25, 2021 · The recently updated 8th edition of the American Joint Committee on Cancer Staging Manual and the 5th edition of the WHO Classification of Digestive System Tumours provide a three-tiered grading system for mucinous appendiceal neoplasms, a unique tumor in situ category for low-grade appendiceal mucinous neoplasms, new descriptions of …
Cannabis Use in Patients With Cancer: A Clinical Review
WEBJun 24, 2022 · Of the 15.5 million Americans living with cancer, 1 moderate to severe pain (0-10 numerical rating score ≥ 5) is experienced by more than a third because of consequences of cancer, its treatments, or both. 2 According to a large, longitudinal study done by the American Cancer Society, pain was among the top three symptoms …
Antiemetics: ASCO Guideline Update | Journal of Clinical Oncology
WEBJul 13, 2020 · The first ASCO guideline for antiemetics was published in 1999, 1 with updates in 2006, 2 2011, 3 2015, 4 and 2017. 5 This update of the 2017 guideline provides guidance on the use of dexamethasone as a prophylactic antiemetic in patients receiving CPIs. This guideline update addresses programmed death-1 (PD-1), programmed death …
Global Radiotherapy: Current Status and Future Directions—White …
WEBJun 8, 2021 · The WHO states that the highest attainable standard of health is a fundamental right of every human being. 1 Factors such as availability, accessibility, acceptability, and quality are fundamental to obtain the highest attainable standard of health. 2 Although there is mounting evidence that good health care can benefit the …
Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO ...
WEBKidney cancer will be diagnosed in 79,000 US patients in 2022 (50,290 men and 28,710 women) and will account for 13,920 deaths (8,960 men and 4,960 women). 1 Clear cell renal cell carcinoma (ccRCC) is the most common subtype of RCC, and it continues to be a major source of morbidity and mortality. 1,2 This disease has been a bellwether tumor …
Updated Diagnostic Criteria and Staging System for Multiple …
WEBMay 19, 2016 · The diagnosis of MM requires 10% or more clonal plasma cells on bone marrow examination or a biopsy-proven plasmacytoma plus the presence of one or more myeloma-defining events. 10 Myeloma-defining events include the presence of one or more CRAB features, or one or more biomarkers of malignancy. The three biomarkers …